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Douglas K. Rex, MD, M������� reviewing Heisser T, et al. Gastroenterology 2020 Aug 7.

This study compared the incidence of advanced neoplasms in 2456 German screening colonoscopy patients who had a previous colonoscopy without polyps to the results from 12,033 first-time screening colonoscopy patients. Among the study objectives, the researchers investigated the prevalence of advanced colorectal neoplasms after colonoscopy intervals beyond 10 years and the potential role of risk stratification.

Douglas K. Rex, MD, M������� reviewing Butterly LF, et al. Am J Gastroenterol 2020 Aug 21.

The American Cancer Society recently recommended that colorectal cancer screening begin at age 45, but the recommendation is not widely followed. In this study with nearly 41,000 patients, data from a colonoscopy registry was used to compare the prevalence of advanced neoplasia in an “average-risk screening equivalent” cohort of individuals aged 45 to 49 years with patients aged 50 to 54 years and older undergoing screening colonoscopy.

Douglas K. Rex, MD, M������� reviewing Kooyker AI, et al. Clin Gastroenterol Hepatol 2020 Aug 7.

Data from nearly 173,000 individuals who underwent follow-up colonoscopy after a positive fecal immunochemical test (FIT) result were evaluated by researchers in this study to understand colonoscopy-related mortality within the Netherlands' national FIT screening program for colorectal cancer.

Douglas K. Rex, MD, M������� reviewing Pilonis ND, et al. Ann Intern Med 2020 May 26.

Previous studies in symptomatic populations have found that a negative colonoscopy predicts a reduction in colorectal cancer incidence for greater than 20 years. The current study examined the impact of a negative screening colonoscopy, specifically the effects of a high-quality examination, in 165,887 individuals who were followed for up to 17.4 years. <br><br> <a href="https://rss.com/podcasts/asgejournalscan/49532">Listen to podcast on this article.</a>

Douglas K. Rex, MD, M������� reviewing Laanani M, et al. Am J Gastroenterol 2020 Apr.

This study evaluated more than 4 million patients undergoing a first-time colonoscopy to assess incidence rates of systemic serious adverse events, including shock, myocardial infection, stroke, pulmonary embolism, acute renal failure, and urolithiasis. Risk factors were also identified.

Douglas K. Rex, MD, M������� reviewing Forbes N, et al. Clin Gastroenterol Hepatol 2020 Mar 20.

In a systematic review and meta-analysis encompassing 27 studies with 11,276,244 colonoscopies, researchers evaluated whether there is an association between procedure volume and adenoma detection rates, cecal intubation rates, adverse events, or postcolonoscopy cancer.

Douglas K. Rex, MD, M������� reviewing Lam AY, et al. Gastrointest Endosc 2020 Feb 21.

A 2017 study from the Polish screening colonoscopy program showed that when doctors improved their adenoma detection rate (ADR), their patients lowered their risk of interval colorectal cancer after colonoscopy. The current study was performed at a single center in the U.S., where in 2010, a quality program was instituted that involved increasing use of split-dose bowel preparation, withdrawal time measurement, ADR measurement, report cards, and educational and corrective sessions.

Douglas K. Rex, MD, M������� reviewing Weiser E, et al. J Med Screen 2020 Feb 13.

This industry-sponsored study examined adherence rates to the fecal immunochemical test-fecal DNA test. The study, which included 368,494 Medicare patients for whom the test was ordered, also reports data on tests ordered and completed, according to the ordering physician specialty.

Douglas K. Rex, MD, M������� reviewing Parsa N, et al. Gastrointest Endosc 2020 Feb 4.

When colonoscopy is incomplete, radiographic studies are often ordered to complete colorectal imaging. In a single U.S. center with a large experience performing colonoscopy in patients with previous incomplete colonoscopies, researchers identified patients who underwent either CT colonography or barium enema within 3 years of the repeat colonoscopy and evaluated the sensitivity of radiographic imaging performed for this purpose.

Douglas K. Rex, MD, M������� reviewing Anderson R, et al. Gastroenterology 2020 Jan 8.

Much of the quality movement in colonoscopy has been directed to preventing interval cancer following colonoscopy. To determine the factors that cause this outcome, researchers reviewed cases of 107 interval cancers at a single medical center, involving 61,110 colonoscopies over an 11-year period with a 3-year interval cancer rate of 4.7%.